%0 Journal Article
%T Association between Cystocele Severity and Coexistent Overactive–Underactive Bladder Syndrome: A Retrospective Analysis
%A Chen Hao
%A Liu Fang
%A Zhao Lin
%J Bulletin of Pioneering Researches of Medical and Clinical Science
%@ 3006-2659
%D 2026
%V 6
%N 1
%R 10.51847/Ug0gbbXWrl
%P 235-241
%X CUOB (coexistent underactive overactive bladder) syndrome describes a clinical picture in which patients experience both storage and voiding difficulties that frequently fail to match the results seen on urodynamic testing. This study aimed to identify how patients with CUOB differ according to the presence or absence of a cystocele. Participants were selected from a total of 2000 women who had received urodynamic testing during the period 2008–2016. Relevant demographic and clinical details were extracted for 369 women whose reported symptoms matched the profile of CUOB. Cohort division was based on the Pelvic Organ Prolapse Quantification System. LUTS severity was measured with the International Consultation on Incontinence Questionnaire Short Form (ICIQ-UI SF). The analysis included 185 women with either no cystocele or only a grade I cystocele (group 1) and 185 women with grade II or III cystocele (group 2). The average age did not differ between the two groups. Body mass index was significantly higher in group 1 (27 vs. 25, P = 0.02). Factors known to increase prolapse risk—such as number of deliveries (1.7 vs. 2.1, P = 0.001) and the heaviest baby weight (3460 g vs. 3612 g, P = 0.049)—were elevated in group 2. Pelvic organ prolapse symptoms appeared 4.5 times more often in group 2 [n = 36/185 (19.5%) vs. n = 162/184 (88%), P < 0.001]. Group 1 demonstrated higher rates of stress urinary incontinence (70.8% vs. 55.4%, P = 0.002), urge urinary incontinence (64.9% vs. 50%, P = 0.04), and elevated ICIQ-UI-SF scores (8 vs. 5, P < 0.001). Maximum urinary flow rate proved lower in group 2 (17 vs. 15 mL/s, P = 0.008). Detrusor pressure during peak flow stayed identical (24 cm H2O). Bladder Contractility Index values were greater in group 1 (108 vs. 96.5, P = 0.017), whereas weak bladder contractions (BCI < 100) occurred more commonly in group 2 (73/185; 39.5% vs. 95/184; 52.7%, P = 0.011). These outcomes indicate that CUOB may benefit from further subdivision depending on whether a cystocele is present. Future studies should investigate the outcomes of prolapse correction surgery in women who have both CUOB and cystocele so that clinicians can provide more accurate guidance to patients.
%U https://bprmcs.com/article/association-between-cystocele-severity-and-coexistent-overactiveunderactive-bladder-syndrome-a-ret-jxfq7spgppglnuw