TY  - JOUR
T1  - Effect of Vanillic Acid and Morin on Bisphenol S and Diethyl Phthalate Induce-Nephrotoxicity in Male Rats
A1  - Ofem Effiom Eteng
A1  - Nseobong Bassey
A1  - Eteng Ibiang Eteng
A1  - Ekam Patrick Okwe
A1  - Grace Ekpo
A1  - Victor Ekam
A1  - Eyong Ubana
JF  - Bulletin of Pioneering Researches of Medical and Clinical Science
JO  - Bull Pioneer Res Med Clin Sci
SN  - 3006-2659
Y1  - 2023
VL  - 2
IS  - 1
DO  - 10.51847/JipHmYy6fi
SP  - 25
EP  - 34
N2  - Endocrine disruptor chemicals (EDCs) have an external influence that has a detrimental effect on the biological system. Morin and vanillic acid has key nephron-pharmacological effects to reduce this effect. We used a rat model to study the impact of Morin and vanillic acid on diethyl phthalate (DEP) and bisphenol S (BPS)- induced nephrotoxicity. After twenty-one days of DEP (50 mg/kg) and BPS (200 mg/kg) exposure and treatment with Morin and vanillic acid (25 and 25 mg/kg), samples were taken for the evaluation of biochemical parameters, including glutathione peroxidase (GPx), glutathione (GSH), catalase activity (CAT), and superoxide dismutase (SOD). Levels of calcium, sodium, urea, and creatinine. Nitric oxide (NO), hydrogen peroxide H202, and malondialdehyde levels (MDA) respectively. The kidney membrane was considerably (P< 0.05) preserved by morin and vanillic acid therapy. In a strikingly significant way (P 
UR  - https://bprmcs.com/article/effect-of-vanillic-acid-and-morin-on-bisphenol-s-and-diethyl-phthalate-induce-nephrotoxicity-in-male-v4e8nuhqwuedm6y
ER  -