%0 Journal Article
%T Immediate Tricuspid Annular Geometric Remodeling After Transcatheter Leaflet Approximation for Tricuspid Regurgitation
%A Bruno Martins
%A Lucas Pereira
%A Renata Azevedo
%A Pedro Costa
%J Bulletin of Pioneering Researches of Medical and Clinical Science
%@ 3006-2659
%D 2025
%V 5
%N 1
%R 10.51847/NLBh2kvhlN
%P 189-196
%X A range of transcatheter devices have been introduced for tricuspid valve procedures in recent times. The present investigation sought to examine acute tricuspid annular reshaping following percutaneous leaflet repair with a device designed to bring leaflets together and diminish tricuspid regurgitation (TR). This retrospective cohort analysis included 26 consecutive subjects managed across two institutions. Intraprocedural three-dimensional transesophageal echocardiography was employed to evaluate tricuspid annular geometry. The cohort’s average age was 79.3 years, with 88.5% of participants being women. Every patient exhibited severe or worse TR before the intervention, principally resulting from annular enlargement. The procedure was successful in all subjects, as documented by an improvement in TR of at least 1 grade before discharge from the hospital. Marked decreases were recorded for the mean septal-lateral dimension (4.09 ± 0.44 cm vs. 3.54 ± 0.53 cm, P < 0.0001), mean major diameter (4.65 ± 0.63 cm vs. 4.28 ± 0.65 cm, P = 0.0002), planimetric area (14.00 ± 2.91 cm² vs. 11.25 ± 2.91 cm², P < 0.0001), and perimeter (13.62 ± 1.43 cm vs. 12.42 ± 1.62 cm, P < 0.0001) of the tricuspid annulus. Within this limited real-world series, transcatheter edge-to-edge repair appeared both efficacious and safe. Deployment of a leaflet approximation device not only lessened TR magnitude but also brought about meaningful contractions in annular measurements. To the best of our understanding, this work provides further confirmation of acute tricuspid annular remodeling following edge-to-edge repair, a finding with noteworthy therapeutic implications.
%U https://bprmcs.com/article/immediate-tricuspid-annular-geometric-remodeling-after-transcatheter-leaflet-approximation-for-tricu-xwxkxq39t5mx3ex