TY  - JOUR
T1  - Immediate Tricuspid Annular Geometric Remodeling After Transcatheter Leaflet Approximation for Tricuspid Regurgitation
A1  - Bruno Martins
A1  - Lucas Pereira
A1  - Renata Azevedo
A1  - Pedro Costa
JF  - Bulletin of Pioneering Researches of Medical and Clinical Science
JO  - Bull Pioneer Res Med Clin Sci
SN  - 3006-2659
Y1  - 2025
VL  - 5
IS  - 1
DO  - 10.51847/NLBh2kvhlN
SP  - 189
EP  - 196
N2  - A range of transcatheter devices have been introduced for tricuspid valve procedures in recent times. The present investigation sought to examine acute tricuspid annular reshaping following percutaneous leaflet repair with a device designed to bring leaflets together and diminish tricuspid regurgitation (TR). This retrospective cohort analysis included 26 consecutive subjects managed across two institutions. Intraprocedural three-dimensional transesophageal echocardiography was employed to evaluate tricuspid annular geometry. The cohort’s average age was 79.3 years, with 88.5% of participants being women. Every patient exhibited severe or worse TR before the intervention, principally resulting from annular enlargement. The procedure was successful in all subjects, as documented by an improvement in TR of at least 1 grade before discharge from the hospital. Marked decreases were recorded for the mean septal-lateral dimension (4.09 ± 0.44 cm vs. 3.54 ± 0.53 cm, P < 0.0001), mean major diameter (4.65 ± 0.63 cm vs. 4.28 ± 0.65 cm, P = 0.0002), planimetric area (14.00 ± 2.91 cm² vs. 11.25 ± 2.91 cm², P < 0.0001), and perimeter (13.62 ± 1.43 cm vs. 12.42 ± 1.62 cm, P < 0.0001) of the tricuspid annulus. Within this limited real-world series, transcatheter edge-to-edge repair appeared both efficacious and safe. Deployment of a leaflet approximation device not only lessened TR magnitude but also brought about meaningful contractions in annular measurements. To the best of our understanding, this work provides further confirmation of acute tricuspid annular remodeling following edge-to-edge repair, a finding with noteworthy therapeutic implications.
UR  - https://bprmcs.com/article/immediate-tricuspid-annular-geometric-remodeling-after-transcatheter-leaflet-approximation-for-tricu-xwxkxq39t5mx3ex
ER  -