The purpose of this research is to ascertain the prevalence of vaginal infections among females in Delta State across various age groups. Samples from female patients at Delta State's Central Hospitals and from women who visited private labs in Sapele, Abraka, Eku, and Oghara were used in the research. In order to detect vaginal infection, urine and higher vaginal swabs (HVS) were collected from 500 female subjects who had clinical signs of vaginitis. 88% of women had infected vaginal illnesses. A total of six (6) organisms were identified, namely; Staphylococcus spp., (54%; n=270), Pseudomonas aeruginosa (18%; n=90), Streptococcus sp., (16%; n=80), Klebsiella spp. (14%; n=70), Candida sp. (12%; n=60), and Escherichia coli (6%; n=30). 12% of the samples were not infected. Of the 500 samples examined, 120 (24%) samples had mixed infections, while 76% (n = 380) had a single infection. Age-wise distribution of the prevalence of vaginal infection reveals that a total of 90 samples were within the age group; of 14–19, with 66.7% appearing positive, 300 samples were within the age group of 20–30 years, with 96.76% (290) being positive, 110 samples were above the age of 30 years, with 81.8% (90) being positive. In this research, vaginal infections were very common. The age range of 20 to 30 years has a higher incidence of vaginal infections.