Written by Bahar Graefen
Published in Vol 2 Issue 2, 2023
Resident doctors regularly suffer burnout because of a wide range of issues, including long working hours, high academic requirements, a lack of independence, balancing their workload and familial responsibilities, low benefits, and anxiety over their future. This is particularly problematic since burnout can increase the probability of medical mistakes and decrease the quality of patient care. This study was conducted in Baku, Azerbaijan, and used a descriptive study design to investigate the s
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Written by Xinyi Chen
Published in Vol 2 Issue 2, 2023
One of the significant aspects of the production of proteins is the discussion of their stability and solubility. Studying the stability of proteins and identifying factors that increase their stability, is one of the important and interesting topics in scientific societies. The production of biotech medicinal proteins plays an important role in the fight against diseases. Proteins are stable only in a limited range of temperature and acidity conditions and are very susceptible to physical and c
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Written by Belén Fernández-Castilla
Published in Vol 2 Issue 2, 2023
Health decisions should be according to the evidence from randomized controlled trials. These studies compare two or more effective interventions in a specific situation on the target population. When for a specific clinical problem in randomized controlled trial studies, the effect of at least three effective interventions is examined, meta-analysis can be used to combine the effect of the interventions and obtain a general estimate of that effect size in the target population; while for most c
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Written by Joshua P. Vogel
Published in Vol 2 Issue 2, 2023
In developing countries, the first cause of maternal mortality is postpartum hemorrhage. Therefore, prevention and treatment of postpartum hemorrhage is an important step in the health of society, especially the health of women. So far, various studies have tried to suggest the best and most effective way to treat postpartum hemorrhage. The present study was conducted to review the studies conducted on medical and non-medical treatments effective on postpartum hemorrhage in Iran and the world. T
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Written by Kasuni Weerasinghe
Published in Vol 2 Issue 2, 2023
A huge amount of data is generated annually in the field of medical care and drug diagnosis. With the continuous growth of data storage tools and the smart devices availability in the world, the big data influence will continue to develop. This efficacy has also been transferred to the field of medicine. The current study was conducted to identify the big data applications in the pharmaceutical field. The present study was done in two stages with a combined approach. In the first step, big data
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Written by Tuba Shahid Chaudhry
Published in Vol 2 Issue 2, 2023
In patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS), vasopressors and inotropes are widely used to stabilize circulation. However, their effect on survival remains uncertain. We performed a systematic review of MEDLINE, EMBASE, and CENTRAL through 20 February 2019, including both randomized and observational studies reporting mortality in AMI-related CS. Eligible studies compared patients receiving at least one vasopressor or inotrope with those who did not r
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Written by Jan H. Willmann
Published in Vol 2 Issue 2, 2023
This systematic review and meta-analysis investigated the clinical outcomes of tooth-borne partial and full-coverage fixed dental restorations produced from hybrid polymer–ceramic CAD/CAM materials, with emphasis on biological, mechanical, and esthetic performance. Literature searches were conducted in MEDLINE using a PICOS framework, and randomized controlled trials as well as case-control studies were screened independently by two reviewers with MeSH terms. Study quality and risk of bias were
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Written by Martin A. Katzman
Published in Vol 2 Issue 2, 2023
While kidney transplantation substantially improves patient outcomes, early post-transplant mortality remains a concern. Growth differentiation factor 15 (GDF-15) has recently been explored as a biomarker for predicting mortality in various clinical contexts. This study investigates whether pretransplant GDF-15 levels can serve as a prognostic indicator in kidney transplant candidates. The analysis included 395 recipients with stored serum samples obtained prior to transplantation. The median GD
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