Written by Sarah Ahmed Al-Twaijri
Published in Vol 4 Issue 1, 2024
Orthodontics has recently used lasers for a broad range of operations. Beyond the previously indicated spectrum of treatments, lasers have emerged as a valuable tool for many soft tissue procedures, replacing traditional scalpel-based techniques in managing soft tissue during orthodontic treatments. Owing to the need for more available data on the latter topic, this research was structured to include clinical studies using laser-assisted soft tissue ablation in orthodontics. Five years (2010-201
Read More
Written by Shahzeb Hasan Ansari
Published in Vol 4 Issue 1, 2024
Zirconia is generally utilized as a framework for the rest of all-ceramic crowns, typically needing feldspar ceramic veneering to achieve suitable esthetics as it offers high opacity. Monolithic zirconia restorations have been presented lately, and their manufacturing process needs attention. This systematic review aimed to determine the difference between monolithic and layered zirconia crowns regarding their clinical success and longevity. A thorough analysis of the literature covering the yea
Read More
Written by Kader Semra Karatas
Published in Vol 4 Issue 1, 2024
Coronavirus disease 2019 (COVID-19) often does not require hospitalization. Various neuropsychiatric findings have been associated with COVID-19 cases that require hospitalization. However, data on psychiatric disorders following outpatient treatment for COVID-19, in cases not requiring hospitalization, are limited. Psychotic disorders are characterized by disturbances in emotion, thought, perception, and speech . T here are many causes associated with neuropsychiatric or psychiatric conditions
Read More
Written by Lauro Figueroa-Valverde
Published in Vol 4 Issue 1, 2024
For several years, prostate cancer has increased worldwide, resulting in a decrease in life expectancy in men. Recently, the World Health Organization reported that this clinical pathology was associated with an increased mortality rate in patients aged 60 to > 60 years. This investigation aimed to analyze some statistical data on prostate cancer in Central and northern Mexico (45 to 64; 65 and ˃ 65 years) populations using the Information System of the Ministry of Health of Mexico. Statistical
Read More
Written by Wiktoria Suchy
Published in Vol 4 Issue 1, 2024
Pain management post-surgery is critical for effective recovery, yet conventional analgesics like opioids, nonsteroidal anti-inflammatory drugs ( NSAIDs), and acetaminophen carry risks of side effects such as nausea and dependency. Transdermal lidocaine patches (LP) have emerged as an alternative, promising localized pain relief with minimal systemic effects. However, the efficacy of LP varies across surgical procedures. In arthroscopic rotator cuff repairs, LP did not significantly reduce pain
Read More
Written by Pei Feng
Published in Vol 4 Issue 1, 2024
Frailty is a kind of clinical state or a kind of complex pathological syndrome characterized by impaired physiological functions, weakened physical and mental resistance to stress, and reduced ability to maintain homeostasis in multiple systems. Several types of risk factors can affect the occurrence and development of frailty either independently or in conjunction with one another, including age, gender, and exercise habits; and multidimensional systemic treatment are often required to alleviat
Read More
Written by Carina Bona
Published in Vol 4 Issue 1, 2024
This study aimed to assess the risk of hyperlactatemia (LA) in patients who received atorvastatin (ATV) treatment. An observational and retrospective study using a case-crossover study design. The participants who received atorvastatin (10 - 80 mg) were included in the sample. The main variable in the study was the total number of treatment days for all the medications administered to each patient (PD). All PDs with lactate>4mmol/L were cases, while all PDs with lactate≤4mmol/L were controls. Th
Read More
Written by Nurul Hannah Jaafar
Published in Vol 4 Issue 1, 2024
The COVID-19 confinement disrupted daily routines and physical activity patterns among Spanish university students. This study investigated musculoskeletal pain, physical activity behaviors, and perceived stress levels in student populations from two universities in Spain during the lockdown. A cross-sectional survey was conducted with 1,198 participants (70.6% women). Data collection involved the Kuorinka M o dified Nordic Questionnaire, the Perceived Stress Scale, and a questionnaire on exerci
Read More
Written by Agung Endro Nugroho
Published in Vol 4 Issue 1, 2024
The primary principle in managing scar contractures is to address the loss of skin that results from releasing the contracted area, which is commonly restored using flaps or skin grafts. However, the unique attributes of scar contractures—including their location, configuration, and extent—differ substantially across patients, making preoperative planning complex. To achieve more predictable and effective outcomes, we formulated a three-dimensional classification framework for these lesions. Thi
Read More
Written by Martin Lange
Published in Vol 4 Issue 1, 2024
The clinical detection of hepatomegaly and splenomegaly—abnormal enlargement of the liver and spleen, respectively—requires a comprehensive evaluation, as numerous underlying conditions may be responsible, including metabolic, congestive, neoplastic, infectious, toxic, or inflammatory etiologies. Within metabolic disorders, lysosomal storage diseases (LSDs) are a rare and ultra-rare group, collectively affecting approximately 1 in 5000 live births. These disorders arise from genetic mutations im
Read More
Written by Sarah Cui
Published in Vol 4 Issue 1, 2024
Depression during pregnancy is widespread and can have serious outcomes. Prior evidence has hinted that antibiotic treatment may be linked to depressive disorders. Because many pregnant individuals receive antibiotics, further study of this potential connection is necessary. This study used data from a nationwide, prospective online survey of pregnant participants in their third trimester. Antenatal depressive symptoms (ADSs) were identified by an Edinburgh Postnatal Depression Scale score of 13
Read More
Written by Rosas-Nexticapa Marcela
Published in Vol 4 Issue 1, 2024
Quality of life (QoL) has become a crucial, non-medical factor for assessing patient care. In hemodialysis treatment, maintaining functional vascular access is essential, as its performance affects not only therapeutic success but also the patient’s overall wellbeing. This underscores the importance of optimizing vascular access care. The present research aimed to determine how patients’ perceptions of their vascular access relate to their quality of life. The study involved 202 hemodialysis pat
Read More
Written by Yuki Tanaka
Published in Vol 4 Issue 1, 2024
The incorporation of anti-thymocyte globulin (ATG) into conditioning regimens to prevent graft-versus-host disease (GVHD) can markedly impair immune reconstitution (IR). We examined the associations among ATG exposure, recipient lymphocyte counts, IR, and post-transplant outcomes. This retrospective study included patients aged ≤18 years who underwent allogeneic hematopoietic stem cell transplantation (HSCT) from April 2005 to April 2020. Outcomes assessed were GVHD incidence, overall survival (
Read More
Written by Daniel M. Hart
Published in Vol 4 Issue 1, 2024
Pulmonary hypertension (PH) is a frequent complication in patients with aortic stenosis (AS) and is generally associated with adverse outcomes. However, the clinical significance of changes in PH following transcatheter aortic valve implantation (TAVI) has not been fully elucidated. We examined data from a prospective, multicenter TAVI registry across six Japanese institutions, estimating pulmonary artery systolic pressure through echocardiographic transtricuspid pressure gradient (TRPG). A tota
Read More
Written by Pedro J. Santos
Published in Vol 4 Issue 1, 2024
Inherited retinal degenerations (IRDs), although uncommon, are the primary cause of blindness among adults of working age. These disorders are genetically complex, involving over 300 different loci, and establishing a molecular diagnosis is crucial for access to emerging therapies and clinical trials. Standard panel-based next-generation sequencing (pNGS) identifies causative variants in approximately 70–80% of cases, leaving a significant subset unresolved. This study examines patients with neg
Read More
Written by Franz K. Müller
Published in Vol 4 Issue 1, 2024
IgA nephropathy (IgAN) ranks among the most prevalent primary glomerular diseases. In traditional Chinese medicine, therapies aimed at supplementing qi, dispelling wind, and promoting blood circulation are frequently employed to manage this condition. Nevertheless, prior research is limited by small sample sizes, making it challenging to draw firm conclusions. This study performed a meta-analysis to systematically evaluate the clinical effectiveness of this approach and provide comprehensive evi
Read More
