Written by Michael Turner
Published in Vol 6 Issue 1, 2026
To investigate how diabetes mellitus (DM) and the use of metformin affect aneurysm sac changes after endovascular aneurysm repair (EVAR). We conducted a retrospective analysis at a single center of a consecutive series of patients who underwent elective EVAR for infrarenal abdominal aortic aneurysm (AAA) from January 2011 through December 2021. Inter-group comparisons were performed, Kaplan–Meier survival curves were generated for both overall survival and freedom from reintervention, and Cox re
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Written by Wei Chen
Published in Vol 6 Issue 1, 2026
This single-center cohort study examined how certain preoperative factors — such as overall physical capability and the size and tissue composition of the quadriceps femoris — relate to physical activity (PA) levels measured 1 year after total knee arthroplasty (TKA). A total of 204 patients with knee osteoarthritis who underwent TKA were included and later divided into two groups based on whether their physical activity increased or decreased. Variables that showed notable differences between t
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Written by Lucas Meyer
Published in Vol 6 Issue 1, 2026
Robotic surgery has seen rapid and widespread uptake among gynecologic surgeons, largely because of its proven capacity to lower patient morbidity. Plastic surgeons must therefore update their reconstructive strategies to fully leverage the advantages of robotic-assisted procedures. This paper describes our clinical outcomes using robotic-assisted rectus abdominis muscle flaps for posterior vaginal wall reconstruction. It includes a review of the existing literature on robotic-assisted reconstru
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Written by Claire Dupont
Published in Vol 6 Issue 1, 2026
Individuals diagnosed with hematologic malignancy (HM) commonly face elevated incidences of thrombocytopenia, thrombocytopathy, anemia, leukopenia, and coagulopathy. These conditions can markedly heighten the likelihood of complications arising during or after medical procedures. The present study was designed to investigate the safety profile and clinical outcomes of percutaneous dilatational tracheostomy (PDT) in critically ill patients with HM. A retrospective cohort analysis was conducted on
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Written by Hiroshi Tanaka
Published in Vol 6 Issue 1, 2026
Tooth shade determination plays a critical role in the overall success of dental restorations, yet visual impairment can negatively affect its accuracy. The objective of this cross-sectional clinical study was to evaluate the potential impact of visual impairment on shade selection by employing two distinct approaches: spectrophotometry and conventional shade guides. The study sample comprised 2796 maxillary and mandibular teeth. Shade selection was assessed subjectively using a shade guide (VIT
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Written by Maria Hernandez
Published in Vol 6 Issue 1, 2026
The current investigation examined the significance of macular pigment optical density (MPOD) in individuals with full-thickness macular hole (FTMH) compared with healthy volunteers. It also aimed to monitor changes in MPOD following surgery and to determine any potential links between these changes and final visual performance. This prospective, cross-sectional, comparative analysis included 16 eyes of patients with FTMH who achieved complete anatomical closure after pars plana vitrectomy with
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Written by Ravi Kumar
Published in Vol 6 Issue 1, 2026
The clinical trial titled “Effect of Modulated Auditory Stimulation on Interaural Auditory Perception” (NCT0544189) sought to determine whether a specific auditory intervention, “Bérard in 10,” could enhance the benefits of routine treatments for patients experiencing anxiety and/or depression. Unblinded, randomized, controlled clinical trial. Mejorada del Campo Health Center, Madrid (Primary Care). A total of 233 patients were selected via systematic sampling and met the following inclusion cri
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Written by Daniel Fischer
Published in Vol 6 Issue 1, 2026
The extraction of spontaneously fractured pacemaker or defibrillator leads whose proximal segments have migrated into the vascular system has received limited detailed analysis to date. This study was designed to evaluate and compare the efficacy of various extraction techniques and supporting tools for fractured leads with migrated proximal ends. A retrospective review was performed on 72 cases selected from a total database of 3847 transvenous lead extraction (TLE) procedures. The majority of
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Written by Claire Martin
Published in Vol 6 Issue 1, 2026
The artificial urinary sphincter represents an effective therapeutic option for stress urinary incontinence resulting from intrinsic sphincter deficiency among women. Nevertheless, adoption of this device remains restricted due to technical challenges and potential risks associated with traditional open surgical implantation. Early investigations using robotic methods have yielded encouraging results; however, only one limited-scale study has directly compared robotic and open techniques. The cu
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Written by Ahmed Mansour
Published in Vol 6 Issue 1, 2026
This research aimed to explore the frequency of atypical or non-classical complications in adult-onset Still’s disease (AOSD), excluding macrophage activation syndrome (MAS), and to identify the factors associated with their occurrence. A multicenter cross-sectional analysis was carried out on AOSD patients listed in the Spanish registry focused on Still’s disease. In total, 107 individuals (67% female) participated in the study, and 64 of them (59.8%) presented with non-classical complications
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Written by Nguyen Thanh Huy
Published in Vol 6 Issue 1, 2026
Continuous vital sign monitoring on general hospital wards enables more frequent, earlier clinical interventions to avert patient deterioration. These interventions can affect clinical outcomes and may themselves serve as markers of impending decline. The present study examines the associations among these clinical actions, established clinical endpoints, and abnormal vital signs. This prospective cohort study included all patients receiving continuous vital sign monitoring on the gastrointestin
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Written by Fatima Zahra Amrani
Published in Vol 6 Issue 1, 2026
Steel wires often prove insufficient for closing the sternum in individuals who face a heightened chance of sternal problems. This investigation evaluates an innovative sternal closure technique against standard steel wires to determine its ability to reduce sternal-related issues and deliver superior patient outcomes. Researchers conducted a retrospective review of 300 consecutive patients who underwent cardiac operations via median sternotomy. Among them, 150 individuals had their sternum clos
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Written by Bruno Martins
Published in Vol 6 Issue 1, 2026
Heart failure (HF) continues to pose a major challenge in public health, where heart transplantation (HT) stands as the definitive treatment for advanced end-stage cases. With the rising adoption of mechanical circulatory support—chiefly left ventricular assist devices (LVADs)—as a bridge to transplant (BTT), clinicians now face more intricate patient situations. The present analysis sought to evaluate extended clinical results among individuals with heart failure with reduced ejection fraction
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Written by Hiroshi Nakamura
Published in Vol 6 Issue 1, 2026
Idiopathic scoliosis (IS) is a common spinal deformity affecting 0.5%-5.2% of children globally, with a broader range in Spain (0.7%–7.5%). Prompt identification through screening programs is vital for preventing mild curves from worsening into serious deformities. Although conventional clinical approaches such as the ADAM test and the trunk rotation angle (TRA) remain standard, recent advances in three-dimensional (3D) surface topography (ST) systems have introduced innovative options for radia
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Written by Maria Gonzalez
Published in Vol 6 Issue 1, 2026
Around 20% of patients experience ongoing chronic pain following total knee arthroplasty (TKA), and high pain catastrophizing stands out as one of the main risk factors. Targeting this adjustable psychological factor before surgery could significantly enhance recovery. The present study compared the impact of two distinct preoperative home-based multimodal physical therapy programs on pain catastrophizing levels among TKA candidates showing high catastrophizing tendencies. A secondary aim was to
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Written by Ahmed El-Kholy
Published in Vol 6 Issue 1, 2026
Fractures of the hip occur frequently in elderly individuals and create a heavy load on healthcare resources owing to elevated morbidity and substantial financial implications. The rising preference for intramedullary nailing in hip fracture repair has inadvertently introduced new hazards; these devices alter bone flexibility and create areas of concentrated stress that may lead to fractures around the implant. This study seeks to analyze the clinical outcomes of peri-implant hip fractures, expl
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Written by Sanjay Kulkarni
Published in Vol 6 Issue 1, 2026
Familial hypercholesterolemia (FH) represents a genetic lipid disorder that frequently triggers premature cardiovascular complications. Subclinical atherosclerosis is characterized by the silent accumulation of fatty plaques within arterial walls well before any overt clinical symptoms emerge. This study explored the prevalence of subclinical atherosclerosis, its arterial distribution, and which factors independently predict its occurrence in people with FH. We conducted a single-center, prospec
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Written by Oliver Grant
Published in Vol 6 Issue 1, 2026
This work aimed to determine whether baseline serum 25-hydroxyvitamin D (25-OHD) concentrations show any link with quality of life (QoL) and pain perception in patients experiencing chronic pain who had been on long-term prescription opioids ahead of planned opioid detoxification. A prospective evaluation was performed on 45 patients with chronic pain maintained on extended prescription opioid therapy and scheduled for elective detoxification. Serum 25-OHD levels were quantified at baseline, bef
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Written by Jinwoo Park
Published in Vol 6 Issue 1, 2026
Outcomes for acute decompensated heart failure (ADHF) in the presence of atrial fibrillation (AF) have historically been unfavorable. The current investigation sought to determine whether catheter ablation (CA) could improve clinical outcomes in individuals with both conditions. A retrospective review was conducted of all ADHF cases involving AF that required admission to our hospital during 2007 through 2017. The analysis ultimately incorporated 472 patients, who were monitored for a mean durat
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Written by Carlos Ramirez
Published in Vol 6 Issue 1, 2026
Sarcopenia is characterized by the progressive loss of muscle mass and strength. This condition frequently coexists with osteoarthritis (OA) in middle-aged women and often intensifies following surgical procedures. Resistance exercise (RE) is known to help reverse sarcopenia, yet muscle function often remains incomplete in many cases. Supplementation with nitrate (NO3−) may offer additional support for muscle repair and work synergistically with RE. The present study evaluated whether adding NO3
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Written by James Walker
Published in Vol 6 Issue 1, 2026
Researchers created a machine learning-based system for predicting mortality risk to overcome difficulties in choosing suitable participants for clinical trials conducted in the Intensive Care Unit (ICU). This algorithm combines Red blood cell Distribution Width (RDW) information with various demographic factors to forecast ICU mortality, working together with established ICU mortality scoring tools such as the Simplified Acute Physiology Score (SAPS). The present study introduces a machine lear
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Written by Ali Hassan
Published in Vol 6 Issue 1, 2026
Although survival rates for childhood cancer have risen considerably, survivors remain at heightened risk for second malignant neoplasms (SMNs), with thyroid cancer being a notable concern. This study explores the demographic, clinical, genetic, and treatment-related profiles of childhood cancer survivors who developed thyroid cancer as a second or third malignancy, underscoring the necessity of extended long-term follow-up. Medical records of childhood cancer survivors treated from 1990 to 2018
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Written by Chen Hao
Published in Vol 6 Issue 1, 2026
CUOB (coexistent underactive overactive bladder) syndrome describes a clinical picture in which patients experience both storage and voiding difficulties that frequently fail to match the results seen on urodynamic testing. This study aimed to identify how patients with CUOB differ according to the presence or absence of a cystocele. Participants were selected from a total of 2000 women who had received urodynamic testing during the period 2008–2016. Relevant demographic and clinical details wer
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Written by Andreas Müller
Published in Vol 6 Issue 1, 2026
Paravalvular leak (PVL) was first noted as a frequent adverse event after transcatheter aortic valve implantation (TAVI) and has often been connected to poorer patient prognosis, such as higher death rates. This investigation aimed to examine the extended clinical consequences of PVL in individuals receiving the most recent models of transcatheter aortic valves, drawing on the national, prospective, multicenter OBSERVANT II registry. The OBSERVANT II registry prospectively collected data on ever
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Written by Maria Silva
Published in Vol 6 Issue 1, 2026
Throat packs are frequently inserted during orofacial operations to reduce postoperative nausea and vomiting (PONV). However, available research offers conflicting results regarding their usefulness, and their application has been connected to complications, including throat discomfort after surgery and the risk of accidental retention. This investigation examined the ability of throat packs to prevent PONV and postoperative sore throat in children with special healthcare needs (SHCNs) receiving
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